"Four Hands" is a piano term that refers to a technique where two people play a single piano together. The drama will depict the friendship, love, rivalry, and growth of youths who meet at an arts high school, following their journey from adolescence to adulthood as professional pianists. Set in an arts high school, the series follows Kang Bi-o, Chae Jeong-yo, and Jae-in as they grow from their school days into adulthood.